Mmmm, what runes would I want if they were real? Two kind of come to mind.
First, increased agility would be cool. This would help with every day tasks and would make life a little easier. Plus, when playing sports I would have an advantage as I would be more agile.
Second, another rune I would want would be better intuition. This would immensely help in my field of work. Because I do scientific research, it would help with determining what experiments to do next and what things needed to be changed.
That's what I can think of now, but I'll see if I can think of more or expand on these more later...have to run to work.